Objetivo: Comparar o implante transcateter de valva aórtica (TAVI) ao tratamento conservador em pacientes inoperáveis ou à cirurgia de troca valvar (SAVR) em pacientes com risco cirúrgico alto ou intermediário conforme a Society of Thoracic Surgeons (STS), por meio de uma revisão sistemática de av...
Objective: Because of preliminary results from in vitro studies, ydroxychloroquine (HCQ) and chloroquine (CQ) have been proposed as possible treatments for COVID-19, but the clinical evidence is discordant. This study aims to evaluate the safety and efficacy of CQ and HCQ for the treatment of COVID-19. M...
Soares, Rodolfo Daniel de Almeida;
Fonseca, Patricia Belintani Blum;
Fertrin, Kleber Yotsumoto;
Marinato, André;
Melo, Andresa Lima;
Nascimento, Ana Clara Kneese;
Moreno, Adrienne Bunn;
Vecina, Antonianna;
Dias, Bruno Vieira;
Lima, Carlos Bernardo Loureiro;
Souza, Fernando Vieira Pericole de;
Cantadori, Lucas Oliveira;
Reis, Marcos Laercio Ponte;
Ganacini, Paulo Roberto;
Helman, Ricardo.
Objective: To report the outcomes of a systematic literature review of guidelines and consensus on the management of paroxysmal nocturnal hemoglobinuria (PNH) and describe the main therapeutic options available worldwide. Methods: A systematic literature review was conducted in April 2018 with no time li...
Objective: This study aims to compare the efficacy and safety of silicone tapes compared to microporous tapes in patients with fragile skin. Methods: A systematic review of the scientific literature was carried out. Clinical trials that compared silicone tape for medical use with the microporous tape in ...